The Philadelphia 76ers will look to turn around their fortunes when they battle the Los Angeles Clippers in a key early-season matchup on Wednesday night. Philadelphia is coming off a 118-116 loss at Phoenix on Monday, while Los Angeles downed San Antonio 113-104 that same night. The 76ers (1-5), the seventh seed last season after going 47-35, are 1-2 on the road this season. The Clippers (3-4), the fourth seed last year at 51-31, are 1-4 on their home court in 2024-25. Los Angeles is still without Kawhi Leonard (knee), while Joel Embiid (suspension) is out for the Sixers. 

Tip-off from the Intuit Dome at Inglewood, Calif., is set for 10 p.m. ET. The 76ers have won four of the last five meetings with Los Angeles. The Clippers are 2-point favorites in the latest 76ers vs. Clippers odds from SportsLine consensus, while the over/under for total points scored is 218.5 (see up-to-date odds for every game this week on our NBA odds page). 

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